Radiesse is an FDA-approved injectable filler renowned for its ability to restore volume and stimulate collagen production in the skin.

Composed of calcium hydroxylapatite microspheres suspended in a gel carrier, Radiesse is designed to provide immediate volume enhancement while stimulating the body’s natural collagen production over time.

Calcium hydroxylapatite is a substance naturally found in our bodies. When used in diluted forms in fillers, it stands out from other fillers by promoting long-term improvements in skin quality, elasticity, tightening, and firmness (Massidda 2023).

1. Long-Lasting Results: Radiesse can provide results that last 12-18 months, and sometimes up to 2-3 years. This is longer-lasting than many other dermal fillers, which typically only last 3-6 months.
2. Collagen Stimulation: Radiesse stimulates the body’s natural production of collagen, which provides the skin with elasticity, strength, and fullness. This collagen stimulation helps maintain the results over time.
3. Immediate Volume and Lift: The calcium hydroxylapatite (CaHA) microspheres in Radiesse provide immediate volume and lift to the treated areas, smoothing wrinkles and folds.
4. Versatility: Radiesse can be diluted with saline to adjust the viscosity, making it suitable for a variety of treatment areas and patient needs. It can be used to treat wrinkles, and volume loss, and contour the face, jawline, and hands.
5. Natural-Looking Results: Radiesse produces natural-looking results by stimulating the body’s collagen production It can reverse signs of aging without making it obvious that cosmetic treatment has been performed.
6. Safety: Radiesse is generally safe and well-tolerated, with minimal risks and side effects. It does not require allergy testing, as the CaHA composition has a low risk of allergic reaction

“Most of the desirable properties of a dermal filler can be achieved with Radiesse, including acceptable longevity, biocompatibility, low rate of side effects, and a reasonable cost-benefit ratio.”

Unlike traditional hyaluronic acid fillers, which primarily add volume through hydration, Radiesse works by providing structural support and stimulating collagen production.

Once injected into the skin, the calcium hydroxylapatite microspheres act as a scaffold, lifting and supporting sagging tissues while the gel carrier provides immediate volume. Over time, the microspheres gradually break down, leaving behind newly formed collagen for long-lasting results.

Radiesse is highly versatile and can address a wide range of aesthetic concerns, including:

1. Wrinkles and Skin Folds: Radiesse can treat moderate to severe facial wrinkles and folds, such as nasolabial folds (the creases from the nose to the corners of the mouth).
2. Volume Loss: Radiesse can restore lost volume in the face, hands, and other areas of the body.
3. Jawline Contouring: Radiesse can be used to contour and define the jawline, providing a more sculpted appearance.
4. Cheek and Midface Contouring: Radiesse can be used to add volume and contour the cheekbones and midface area.
5. Lip Lines: Radiesse can be used to soften and reduce the appearance of lines around the lips.
6. Upper Arm Contouring: Radiesse has been shown to be an effective treatment for improving the appearance and contours of the upper arms.

The Radiesse procedure is quick and relatively painless, typically lasting around 15 to 30 minutes.

Before the treatment, a topical numbing cream may be applied to minimize discomfort. Using a fine needle, the filler is injected into the targeted areas with precision and expertise.

Patients can resume their normal activities immediately following the procedure, with minimal downtime.

While individual results may vary, most patients can enjoy the benefits of Radiesse for up to 12 to 18 months. Over time, the body naturally metabolizes the filler, but the collagen-stimulating effects can last even longer, providing ongoing improvement in skin texture and elasticity.

While Radiesse is generally well-tolerated, some individuals may experience temporary side effects. These effects are typically mild and resolve on their own within a few days.

• Redness, swelling, bruising, itching, pain, or discomfort.
• Nodules or bumps can occur, especially in the hands, with temporary difficulty in hand movements.
• Temporary loss of sensation or numbness may happen, particularly in the hands.
• Rare cases of severe side effects, like blood vessel occlusion, are possible but uncommon.

Radiesse represents a revolutionary approach to facial rejuvenation, offering immediate and long-lasting results with minimal downtime.

With its ability to restore volume, contour facial features, and stimulate collagen production, Radiesse has become a pivotal treatment in aesthetic medicine, empowering individuals to restore their youthful vitality with confidence and grace.

Massidda E. Starting Point for Protocols on the Use of Hyperdiluted Calcium Hydroxylapatite (Radiesse®) for Optimizing Age-Related Biostimulation and Rejuvenation of Face, Neck, Décolletage and Hands: A Case Series Report. Clin Cosmet Investig Dermatol. 2023 Nov 29;16:3427-3439. doi: 10.2147/CCID.S420068. PMID: 38050476; PMCID: PMC10693750.

Jacovella PF. Use of calcium hydroxylapatite (Radiesse) for facial augmentation. Clin Interv Aging. 2008;3(1):161-74. doi: 10.2147/cia.s2065. PMID: 18488886; PMCID: PMC2544361.

Healthline. Radiesse: What You Need to Know. https://www.healthline.com/health/radiesse#procedure.

Merz Aesthetics. Radiesse: A Dermal Filler Treatment. https://www.merzaesthetics.ca/solutions/radiesse/.

Short Hills Dermatology. What Are the Side Effects of Radiesse? https://shorthillsderm.com/blog/dermatology/what-are-the-side-effects-of-radiesse/.

Midlands Dermatology. Radiesse Treatment at Midlands Dermatology. https://www.midlandsderm.com/services/radiesse/.

Oprah Daily. The Benefits of Radiesse Filler: Everything You Need to Know. https://www.oprahdaily.com/beauty/a41793502/benefits-radiesse-filler/.